Vanco Calculator
Calculate vancomycin dosing based on weight, creatinine clearance, and desired trough levels. Provides recommended loading dose, maintenance dose, and dosing interval.
Published by:
isCalculator Editorial Team
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How to Use the Vanco Calculator
This calculator estimates vancomycin dosing based on renal function (CrCl). All inputs are in metric units.
- Enter Weight (kg) – Use actual or ideal body weight as selected below.
- Enter Age (years) – Required for CrCl calculation.
- Enter Serum Creatinine (mg/dL) – Must be >0.1.
- Select Gender – Affects CrCl (females have 0.85 multiplier).
- Choose Desired Trough – 10-15 mg/L for mild infections, 15-20 mg/L for serious.
- Select Weight Type – Actual or ideal body weight.
- Click Calculate.
Outputs:
- CrCl (mL/min) – Renal clearance estimate.
- Loading Dose (mg) – 25-30 mg/kg based on trough target.
- Maintenance Dose (mg) – Fixed at 15 mg/kg.
- Interval (hours) – Based on CrCl: ≥60 = q12h, 30-59 = q24h, 15-29 = q24h, <15 = q48h.
Note: Always verify with clinical guidelines and adjust for individual patient factors.
Previous Results
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Frequently Asked Questions
The Cockcroft-Gault formula estimates creatinine clearance (CrCl) using serum creatinine, age, weight, and gender: CrCl (mL/min) = ((140 - age) * weight) / (72 * SCr) multiplied by 0.85 for females.
Loading dose is typically 25-30 mg/kg of actual body weight. For mild infections (target trough 10-15 mg/L), use 25 mg/kg. For serious infections (target 15-20 mg/L), use 30 mg/kg.
Dosing intervals depend on renal function: CrCl ≥60 mL/min: q12h; CrCl 30-59: q24h; CrCl 15-29: q24h; CrCl <15: q48h or per further adjustment.
