Carboplatin Calculator

Calculate the carboplatin dose using the Calvert formula based on AUC, age, weight, and serum creatinine.

isCalculator Editorial Team Published by:
Reviewed by: Review Board
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How to use this tool?

How to use the Carboplatin Dose Calculator

  1. Enter Target AUC (mg/mL·min): Typically 5–7, as prescribed (range: 0.5–10).
  2. Enter Age (years): Must be 18–120.
  3. Enter Weight (kg): Use metric only; range 30–300 kg.
  4. Enter Serum Creatinine (mg/dL): Range 0.1–10 mg/dL.
  5. Select Gender: Female or Male (affects CrCl calculation).
  6. Click Calculate Dose.

What it does:

  • Calculates creatinine clearance (CrCl) using the Cockcroft-Gault formula.
  • Applies the Calvert formula: Dose = AUC × (CrCl + 25).
  • Outputs the carboplatin dose in mg and shows step-by-step math.

All inputs are required and must be within the specified ranges. Use metric units only.

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Frequently Asked Questions

The Calvert formula calculates carboplatin dose: Dose (mg) = Target AUC × (CrCl + 25), where CrCl is creatinine clearance estimated by the Cockcroft-Gault equation.

CrCl is calculated using the Cockcroft-Gault formula: For males: ((140 - age) × weight) / (72 × serum creatinine). For females: multiply the result by 0.85.

Common target AUC values range from 4 to 6 mg/mL·min, depending on the treatment protocol and patient condition. Always follow your oncologist's prescription.

Reviewed by Experts

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Anita Leonor F. Jaime

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Dedicated Occupational Physician with experience in Occupational Medicine and emergency care. Proficient in health assessments, hygiene management, and compliance with safety standards. Committed to promoting occupational health and improving workplace quality of life.

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Dr. Leonilde Melgaço

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Dr. Zouheir Ballouk

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Layla Nesr

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Neil Chaves

Neil Chaves

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